MedList - Chris Aiken, MD

[Wellbutrin] First-line for depression (lacks weight-gain, sexual, cognitive, fatigue SEs; lack of WD). Safest antidepressant in bipolar. Treats nicotine but…

First line depression Major Depression Restless leg syndrome Treatments Depression Deepen Sleep Nicotine Methamphetamine ADHD Inflammatory Depression

Generic Activating Non-sedating Weight-Free Medication Sexual-free Elderly-Safe Tolerable Weight Loss Non-controlled

Trazodone

Deepens sleep quality in low doses, but under-utlilized as an antidepressant, where it can be very effective and tolerable if…

Hypnotics in Sleep Apnea Agitation in Dementia Hypnotics Major Depression Depression Treatments Bulimia Sleep apnea Deepen Sleep Negative symptoms Sleep

Tolerable Weight-Free Non-controlled Sexual-free Generic Sedating Medication

Rhodiola rosea

Herb that helps with mild depression and stress management….

Major Depression Generalized Anxiety Depression Treatments Anxiety Non-specific Anxiety Anxious Depression

Non-controlled Natural Bipolar-Safe Weight-Free Elderly-Preferred Sexual-free Generic Non-sedating Elderly-Safe Tolerable

Omega 3 (Fish oil)

[Fish oil] For bipolar/unipolar depression [2], ADHD, [3], borderline pd [2], irritability, autism, [2], prevention of psychosis [1], dyslipidemia….

Tolerable Non-controlled Natural Weight-Free Bipolar-Safe Sexual-free Child-Studied Weight Loss Generic Non-sedating Elderly-Safe

Duloxetine

[Cymbalta] Approved for child anxiety. Risk of urine retention (but treats urine incont). Liver risk….

Fibromyalgia Major Depression Generalized Anxiety Treatments Panic Depression Binge Eating Anxiety Chronic Pain Migraines

Child-Studied Medication Generic Child-Approved Tolerable Non-controlled

Venlafaxine

[Effexor] Not ideal among the SNRIs (hypertension, WD risks, weight gain), but very effective for some and treats hot flashes…

Major Depression Generalized Anxiety Panic Depression Treatments Anxiety Social Anxiety Chronic Pain PTSD Migraines Hot flashes

Generic Medication Tolerable Non-controlled

Palmitoylethanolamide

[PEA] For mania [3], and augments antidepressants in unipolar [3], autism, neg symptom schizophrenia, migraines and chronic pain….

Major Depression Depression Treatments Autism Bipolar Chronic Pain Mania Mixed Migraines Negative symptoms Long COVID

Elderly-Safe Tolerable Weight-Free Non-controlled Sexual-free Bipolar-Safe Generic

Fluoxetine

[Prozac] Best SSRI for children, weight loss, low WD risk, and bulimia….

Major Depression Generalized Anxiety First line depression Treatments Depression Bulimia Panic Binge Eating Anxiety Social Anxiety PTSD OCD Borderline Premenstrual Dysphoria Eating Disorders

Medication Weight-Free Child-Approved Tolerable Non-controlled Child-Studied Generic

Fluvoxamine

[Luvox] Only approved in OCD….

Depression Treatments Social Anxiety OCD

Child-Approved Tolerable Non-controlled Child-Studied Generic Medication

Levomilnacipran

[$ Fetzima] Most noradrenergic of the SNRIs, good for fatigue, with side effect profile similar to bupropion. Isomer of milnacipran (used…

Fibromyalgia Major Depression Depression Treatments Chronic Pain Hot flashes

Non-controlled Activating Non-sedating Medication Tolerable

Pramipexole

[Mirapex] Dopamine agonist with powerful benefits in unipolar and bipolar depression, also restless leg syndrome….

Major Depression First line BP depression BP Depression Depression Bipolar Restless leg syndrome Treatment Resistant Depression Inflammatory Depression

Medication Tolerable Generic Non-controlled Weight-Free Sexual-free Sedating

Enlyte

Multivitamin with methylfolate, omega-3, and more. Large effect in depression [1]…

Major Depression BP Depression Depression Treatments Age-related or non-specific decline Treatment Resistant Depression Peripartum Depression Inflammatory Depression

Non-sedating Elderly-Safe Child-Approved Tolerable Non-controlled Natural Weight-Free Bipolar-Safe Sexual-free Elderly-Preferred

Gepirone

[$ Exxua] Similar to buspirone but not as useful (costly, requires EKG testing, failed in most depression trials)…

Major Depression Generalized Anxiety Treatments Depression Anxiety Anxious Depression

Non-sedating Medication Tolerable Non-controlled Sexual-free

Selegiline

[$ EMSAM] Skin patch MAOI, good to start with (low dose = no food interactions) but not as potent as…

Major Depression Depression Treatments Panic Anxiety

Non-controlled Weight-Free Sexual-free Activating Non-sedating Medication Elderly-Safe Tolerable

Escitalopram

[Lexapro] First-line SSRI (no drug interactions, good efficacy in depression/anxiety)….

Generalized Anxiety First line depression Major Depression Depression Treatments Panic Social Anxiety OCD Borderline Hot flashes

Non-controlled Elderly-Preferred Child-Studied Medication Generic Elderly-Safe Child-Approved Tolerable

Vortioxetine

[$ Trintellix] Improves cognition. First-line for depression (lacks weight gain, sexual, fatigue SEs; lack of WS). Well studied in elderly….

Major Depression First line depression Depression Age-related or non-specific decline Treatments Negative symptoms

Non-controlled Elderly-Preferred Sexual-free Non-sedating Medication Tolerable

Buspirone-melatonin combo

Low doses of both treated depression in one trial….

Major Depression Depression Treatments

Sedating Medication Elderly-Safe Tolerable Non-controlled Generic Weight-Free Sexual-free

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