Venlafaxine
[Effexor] Not ideal among the SNRIs (hypertension, WD risks, weight gain), but very effective for some and treats hot flashes in low doses.
[Effexor] Not ideal among the SNRIs (hypertension, WD risks, weight gain), but very effective for some and treats hot flashes in low doses.
Most noradrenergic of the SNRIs, good for fatigue, with side effect profile similar to bupropion. Isomer of milnacipran (used in fibromylagia). Depression [2].
Well-studied in depression [1], sleep, cognition. Small trials in ADHD [3], OCD [3], weight loss [3], sexual dysfunction [3].
[Paxil] Poor choice as SSRI (higher sexual/weight SE, anticholinergic, pregnancy and WD risks).