Memantine
[Namenda] Trichotillomania [1]. First-line for mod-severe Alzheimers (and Lew-Body, Parkinsons dementia). Possibly OCD, alcohol use, bipolar depression [3], autism [2].
OCD
TMS
One of the most effective therapies for TRD. Well tolerated, improves cognition and neuroplasticity.
N-acetylcysteine
[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.
Amitriptyline
[Elavil] Third-line tricyclic, mix of serotonin/noripineprhine, more anticholinergic side effects.
Useful for pain and IBS.
Aripiprazole
[Abilify] Among the better-tolerated antipsychotics, and best-studied for antidepressant
augmentation [1] (but doesn't treat bp-depression). Schizophrenia [1]
Quetiapine
[Seroquel] Unique antipsychotic – metabolized into an antidepressant so treats unipolar
depression (and GAD) as monotherapy. Top for TRD [1]. Deepens sleep. Tolerability poor, but among the most
effective options for BP-depression [1], BP-anxiety [2], mania, mixed.
l-Theanine
Extract of green tea. Depression [3], sleep [2], schizophrenia (neg/anx) [2], OCD [3], cognition [3].
Saffron
Well-studied in depression [1], sleep, cognition. Small trials in ADHD [3], OCD [3], weight loss [3], sexual dysfunction [3].
l-Carnosine
For depression [3], ADHD [3], OCD [3], cognition [3], schizophrenia negative symptoms [3],