cyproheptadine
Similar to mirtazapine, for anorexia [2], alcohol (with prazosin) [2], sleep [4], nightmares [4], sexual dysfunction [3].
Substance Use Disorders
TMS
One of the most effective therapies for TRD. Well tolerated, improves cognition and neuroplasticity.
CBD
[Cannabidiol] This “healthier”strain of cannabis is #1 for cannabis use disorder, but questionable in anxiety and insomnia. Watch for drug interactions.
Magnesium
Improves sleep (with melatonin), bruxism, and essential for liver health in alcohol use disorder.
Tirzepatide
[$ Mounjaro, Zepbound] Most effective of the GLPs for weight loss (use if BMI >30 or > 27 with complications of obesity).
N-acetylcysteine
[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.
Varenicline
[Chantix] The most effective therapy for nicotine, generally safe in psychiatric disorders
Semaglutide
[$ Ozempic, Wegovy] Medium effective of the GLPs for weight loss (use if BMI >30 or > 27 with complications of obesity).