Propranolol
Augments SSRIs in panic, use for tremor, akathisia, and irritability.
Migraines
Nortriptyline
[Pamelor] First-line tricyclic, low sedation/anticholinergic/hypotension risk. More
noradrenergic.
Amitriptyline
[Elavil] Third-line tricyclic, mix of serotonin/noripineprhine, more anticholinergic side effects.
Useful for pain and IBS.
Venlafaxine
[Effexor] Not ideal among the SNRIs (hypertension, WD risks, weight gain), but very effective for some and treats hot flashes in low doses.
Duloxetine
[Cymbalta] Approved for child anxiety. Risk of urine retention (but treats urine incont). Liver
risk.
Melatonin
Hypnotic with particular benefits in elderly and children with developmental disorders [1], and antipsychotic weight loss [1].
Palmitoylethanolamide
[PEA] For mania [3], and augments antidepressants in unipolar [3], autism, neg symptom schizophrenia, migraines and chronic pain.
Palmitoylethanolamide Read More »
Omega 3 (Fish oil)
[Fish oil] For bipolar/unipolar depression [2], ADHD, [3], borderline pd [2], irritability, autism, [2], prevention of psychosis [1], dyslipidemia.
Omega 3 (Fish oil) Read More »
Guanfacine
[Intuniv] Approved for ADHD [2], less sedating than clonidine but not as useful in comorbidities. Tics.
Clonidine
[Kapvay] Approved for ADHD, but also helps mania, nicotine/opioid, anxiety, irritability, self-harm, autism, negative symptoms schizophrenia, tics