Phosphatidylserine
[PS] ADHD [3], cognitive decline [2].
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Tolerable
Palmitoylethanolamide
[PEA] For mania [3], and augments antidepressants in unipolar [3], autism, neg symptom schizophrenia, migraines and chronic pain.
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Lavender
[Silexan] First-line for generalized anxiety, Prescription and approved outside US. Well-tolerated, safe in bipolar.
Omega 3 (Fish oil)
[Fish oil] For bipolar/unipolar depression [2], ADHD, [3], borderline pd [2], irritability, autism, [2], prevention of psychosis [1], dyslipidemia.
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Xanomeline-trospium
[$ Cobenfy] First-line antipsychotic for schizophrenia (lacks long-term risks, though GI issues a problem at start). Not effective in other disorders.
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Guanfacine
[Intuniv] Approved for ADHD [2], less sedating than clonidine but not as useful in comorbidities. Tics.
Clonidine
[Kapvay] Approved for ADHD, but also helps mania, nicotine/opioid, anxiety, irritability, self-harm, autism, negative symptoms schizophrenia, tics