Child-Studied Archives - Chris Aiken, MD

Folinic Acid

[Leucovorin] FDA-approved for autism, addresses a known mechanism there.

Memantine

Autism, BP Depression, Treatments, Dementia, OCD, Mixed, Trichotillomania / Chris

[Namenda] Trichotillomania [1]. First-line for mod-severe Alzheimers (and Lew-Body, Parkinsons dementia). Possibly OCD, alcohol use, bipolar depression [3], autism [2].

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Ginseng

Rapid benefits in energy, cognition, and ADHD that also build up over time (without tolerance or withdrawal).

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Dark-Therapy

Hypnotics, Hypnotic for Elderly, Weight Gain, Treatments, Deepen Sleep, Mania, Mixed, Peripartum Depression, BP Cognition / Chris

Very effective for mania, prevents bipolar, deepens sleep. Mild weight loss.

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Dawn-Simulator

Hypnotics, Depression, Treatments, Hypnotic for Elderly, Deepen Sleep / Chris

Improves morning fatigue and depression, particularly in winter. Can pair with lightbox for depression. Ideal for shift workers and night owls.

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Lightbox

First line depression, Fibromyalgia, Treatments, Depression, Bulimia, BP Depression, Male, Treatment Resistant Depression, Deepen Sleep, PTSD, Peripartum Depression, Negative symptoms, Vascular Depression / Chris

Very effective and well tolerated for depression regardless of season (also for bipolar, PTSD, bulimia, shift work)

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TMS

BP Depression, Treatments, Treatment Resistant Depression, Nicotine, OCD, Vascular Depression, Inflammatory Depression / Chris

One of the most effective therapies for TRD. Well tolerated, improves cognition and neuroplasticity.

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N-acetylcysteine

Treatments, Alcohol, BP Depression, Age-related or non-specific decline, Bipolar, Nicotine, OCD, Trichotillomania, Cannabis, Negative symptoms, Borderline, Inflammatory Depression, Cognition, Substance Use Disorders, Schizophrenia / Nancy Brandon

[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.

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Clomipramine

Major Depression, Treatments, Panic, OCD / Nancy Brandon

[Anafranil] Highly serotonergic, very effective for OCD (tricyclic).

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Duloxetine

Major Depression, Generalized Anxiety, Fibromyalgia, Depression, Treatments, Panic, Anxiety, Binge Eating, Chronic Pain, Migraines / Nancy Brandon

[Cymbalta] Approved for child anxiety. Risk of urine retention (but treats urine incont). Liver
risk.

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