Ginseng
Rapid benefits in energy, cognition, and ADHD that also build up over time (without tolerance or withdrawal).
Activating
Dawn-Simulator
Improves morning fatigue and depression, particularly in winter. Can pair with lightbox for depression. Ideal for shift workers and night owls.
Lightbox
Very effective and well tolerated for depression regardless of season (also for bipolar, PTSD, bulimia, shift work)
Milnacipran
[$ Savella] Approved for fibromylagia in US and depression abroad (parent compound of
levomilnacipran).
Levomilnacipran
[$ Fetzima] Most noradrenergic of the SNRIs, good for fatigue, with side effect profile similar to
bupropion. Isomer of milnacipran (used in fibromylagia).
Solriamfetol
[$ Sunosi] Approved for narcolepsy but has bupropion-like properties and may treat ADHD.
Thyroid T4
[Synthroid] Use for hypothyroidism on lithium. For augmentation in depression, T3 is preferred.
Thyroid T3
[Cytomel] For treatment-resistant bipolar/unipolar depression, well-tolerated and may actually improve manic or anxious symptoms
Selegiline
[$ EMSAM] Skin patch MAOI, good to start with (low dose = no food interactions) but not as potent as older MAOIs.
Acetyl-l-carnitine
[ALC] Depression, especially recurrent/TRD, history of child-trauma, or with medical illness or elderly [2]. Alcohol (mood/memory/cravings) [2]
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