Fluoxetine (Prozac)
SSRI antidepressant
- Major Depression
- Best SSRI For Children
- Generalized anxiety
- PTSD
- Panic
- Bulimia
- OCD
- Binge Eating
Features
Dosing
Depression (20), Anxiety disorders (40-60), Bulimia (60), Binge eating (40-60), Borderline PD (20-60), OCD (60-80).
Management
Side effects: apathy, sexual dysfunction, sleep disruption, nausea, restless legs, akathisia. Warning: osteopenia in post-menopausal women. Raises lots of drug levels by inhibiting CYP 2D6, 3A4, 2C9, 2C19, 2B6.
Best antidep in children. Long half-life (lasts up to a month after stopping it, so lower WD risk than other SSRIs). Less weight gain than other SSRIs. Combined with olanzapine in unipolar and bipolar depression.
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