Magnesium
Improves sleep (with melatonin), bruxism, and essential for liver health in alcohol use disorder.
Alcohol
Tirzepatide
[$ Mounjaro, Zepbound] Most effective of the GLPs for weight loss (use if BMI >30 or > 27 with complications of obesity).
N-acetylcysteine
[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.
Varenicline
[Chantix] The most effective therapy for nicotine, generally safe in psychiatric disorders
Semaglutide
[$ Ozempic, Wegovy] Medium effective of the GLPs for weight loss (use if BMI >30 or > 27 with complications of obesity).
Acetyl-l-carnitine
[ALC] Depression, especially recurrent/TRD, history of child-trauma, or with medical illness or elderly [2]. Alcohol (mood/memory/cravings) [2]
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Pregabalin
[Lyrica] Approved outside US for generalized and social anxiety disorders [1]. Benzo WD, OCD [3], fibromylagia [1].
Gabapentin
[Neurontin] For social anxiety, stabilizing sleep in alcoholics, RLS, akathisia, non-specific anxiety. Better tolerated than pregabalin but less effective.