Hydroxyzine
[Vistaril] A better tolerated prescription version of diphenhydramine (Benadryl) for anxiety and insomnia.
Sleep
Bupropion
[Wellbutrin] First-line for depression (lacks weight-gain, sexual, cognitive, fatigue SEs; lack of WD). Safest antidepressant in bipolar. Treats nicotine but not as well as varenicline. Treats ADHD a little; RLS.
Gabapentin
[Neurontin] For social anxiety, stabilizing sleep in alcoholics, RLS, akathisia, non-specific anxiety. Better tolerated than pregabalin but less effective.
Trazodone
Deepens sleep quality in low doses, but under-utlilized as an antidepressant, where it can be very effective and tolerable if dosed at night.
Suvorexant
[$ Belsomra] Orexin antagonist, improves next-day cognition, low abuse potential, low fall risk. Ideal for elderly. However, daridorexant and lemborexant more effective.
Lemborexant
[$ Dayvigo] Orexin antagonist, improves next-day cognition, low abuse potential, low fall risk. Ideal for elderly.
Daridorexant
[$ Quviviq] Orexin antagonist, improves next-day cognition, low abuse potential, low fall risk. Ideal for elderly.
Ramelteon
[Rozerem] Safe hypnotic that may improve depression in bipolar disorder. Think of it as a potent melatonin.