SAMe
For depression, improves liver health, osteoarthritis, but l-methylfolate has a similar mechanism and better evidence.
For depression, improves liver health, osteoarthritis, but l-methylfolate has a similar mechanism and better evidence.
Well-studied in depression [1], sleep, cognition. Small trials in ADHD [3], OCD [3], weight loss [3], sexual dysfunction [3].
[Cialis] Best of the PDE class for sexual dysfunction on SSRI/SNRI [longer half-life allows spontaneity]
Treats anxiety (GAD). Augments in depression but only if anxious. Also improves sexual dysf, bruxism, irritability, PMDD