Ginseng
Rapid benefits in energy, cognition, and ADHD that also build up over time (without tolerance or withdrawal).
Male
Lightbox
Very effective and well tolerated for depression regardless of season (also for bipolar, PTSD, bulimia, shift work)
Saffron
Well-studied in depression [1], sleep, cognition. Small trials in ADHD [3], OCD [3], weight loss [3], sexual dysfunction [3].
Amantadine
Similar to ketamine. Treats TD [2] and irritability in TBI [1]. Last-line secret-weapon for bipolar/unipolar depression, OCD, cognition, DMDD, autism, weight-loss, fatigue.
Tadalafil
[Cialis] Best of the PDE class for sexual dysfunction on SSRI/SNRI [longer half-life allows spontaneity]