Treatment Resistant Schizophrenia

Clozapine

Bipolar, Treatments, Treatment Resistant Schizophrenia, Mania, Mixed, Psychotic symptoms, Negative symptoms, Schizophrenia / Nancy Brandon

[Clozaril] Use in schizophrenia/schizoaffective after 2 failed antipsychotic trials. Prevents suicide
in psychotic disorders.

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Olanzapine

Bipolar, Treatments, Second line schizophrenia, Treatment Resistant Schizophrenia, Psychotic Depression, Mania, Psychotic symptoms, Mixed, Schizophrenia / Nancy Brandon

[Zyprexa] High efficacy in schizophrenia [2], so use before moving to clozapine. Mania [2], augmentation in unipolar [3], PTSD [3].

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Topiramate

Bulimia, Treatments, Weight Gain, Alcohol, Treatment Resistant Schizophrenia, Anxiety, Binge Eating, Augmentation, OCD, PTSD, Migraines, Borderline, Methamphetamine, Negative symptoms, Cocaine, Eating Disorders, Substance Use Disorders, Schizophrenia / Nancy Brandon

[Topamax] PTSD [2], alcohol [2], bulimia [1], borderline/aggression [3], weight [2], OCD [3], meth [1], cocaine [2], gambling [2], schizophrenia aug [1] migraines

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