Schizophrenia Archives - Page 2 of 4

Ziprasidone

Bipolar, Treatments, Sleep apnea, Treatment Resistant Depression, Mania, Psychotic symptoms, Mixed, Schizophrenia / Nancy Brandon

[Geodon] Among best antipsychotics for low weight/diabetes risk. Treats mania/mixed; possibly
helps depression in unipolar and bipolar.

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Olanzapine

Second line schizophrenia, Bipolar, Treatments, Treatment Resistant Schizophrenia, Psychotic Depression, Mania, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[Zyprexa] High efficacy in schizophrenia [2], so use before moving to clozapine. Mania [2], augmentation in unipolar [3], PTSD [3].

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Lurasidone

BP Depression, Bipolar, Treatments, Mixed, Psychotic symptoms, BP Cognition, Schizophrenia / Nancy Brandon

[Latuda] BP-depression [1], depression with mixed features. Improves cognition in bipolar. Does not treat mania.

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Lumateperone

BP Depression, Bipolar, Treatments, Treatment Resistant Depression, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[$ Caplyta] Among best tolerated antipsychotics for BP-depression [1], also unipolar-depression [2].
Unknown if helps mania. Low dopamine-blocking so well-tolerated in schizophrenia.

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Quetiapine

Generalized Anxiety, Bipolar, Treatments, BP Depression, Anxiety, Treatment Resistant Depression, Deepen Sleep, First line mania, OCD, Mania, Psychotic symptoms, Anxious Depression, Mixed, BP Anxiety, Schizophrenia / Nancy Brandon

[Seroquel] Unique antipsychotic – metabolized into an antidepressant so treats unipolar
depression (and GAD) as monotherapy. Top for TRD [1]. Deepens sleep. Tolerability poor, but among the most
effective options for BP-depression [1], BP-anxiety [2], mania, mixed.

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