Sertraline
[Zoloft] Good choice overall, best SSRI for heart disease, no CYP drug interactions below 150mg.
Major Depression
Paroxetine
[Paxil] Poor choice as SSRI (higher sexual/weight SE, anticholinergic, pregnancy and WD risks).
Zuranolone
[$ Zurzuvae] First-line for post-partum depression, but not for regular depression or post-partum psychosis. Safe in bipolar. 2-week course; benzo-like properties.
Gepirone
[$ Exxua] Similar to buspirone but not as useful (costly, requires EKG testing, failed in most depression trials)
Nefazodone
[Serzone] Last-line antidepressant (a less sedating version of trazodone, but liver risks)
Trazodone
Deepens sleep quality in low doses, but under-utlilized as an antidepressant, where it can be very effective and tolerable if dosed at night.