Inflammatory Depression Archives

TMS

Treatments, BP Depression, Treatment Resistant Depression, Nicotine, OCD, Vascular Depression, Inflammatory Depression / Chris

One of the most effective therapies for TRD. Well tolerated, improves cognition and neuroplasticity.

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N-acetylcysteine

Alcohol, BP Depression, Age-related or non-specific decline, Bipolar, Treatments, Nicotine, OCD, Cannabis, Trichotillomania, Borderline, Negative symptoms, Cognition, Inflammatory Depression, Substance Use Disorders, Schizophrenia / Nancy Brandon

[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.

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Nortriptyline

Major Depression, Depression, Treatments, Treatment Resistant Depression, Deepen Sleep, Psychotic Depression, Migraines, Inflammatory Depression / Nancy Brandon

[Pamelor] First-line tricyclic, low sedation/anticholinergic/hypotension risk. More
noradrenergic.

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Probiotics

Major Depression, Generalized Anxiety, Female, Autism, Bipolar, Depression, BP Depression, Age-related or non-specific decline, Treatments, Anxiety, Deepen Sleep, Treatment Resistant Depression, Anxious Depression, Peripartum Depression, Borderline, Negative symptoms, Sleep, ADHD, Long COVID, Inflammatory Depression, Cognition, Schizophrenia, Sexual Dysfunction / Nancy Brandon

For bipolar/unipolar depression [2], ADHD [3], anxiety [2], cognition [2], autism [2], weight loss [1], dyslipidemia, long COVID [1].

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SAMe

Major Depression, Fibromyalgia, Treatments, Depression, SSRI-Induced, Treatment Resistant Depression, Inflammatory Depression, Sexual Dysfunction / Nancy Brandon

For depression, improves liver health, osteoarthritis, but l-methylfolate has a similar mechanism and better evidence.

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L-methylfolate

Major Depression, Depression, Treatments, BP Depression, Negative symptoms, Inflammatory Depression, Schizophrenia / Nancy Brandon

[Deplin] Medium effect in depression augmentation [1], may help bipolar depression as well.

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Enlyte

Major Depression, Depression, Treatments, Age-related or non-specific decline, BP Depression, Treatment Resistant Depression, Peripartum Depression, Inflammatory Depression / Nancy Brandon

Multivitamin with methylfolate, omega-3, and more. Large effect in depression [1]

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Curcumin

Major Depression, Depression, Treatments, Age-related or non-specific decline, Dementia, Long COVID, Inflammatory Depression / Nancy Brandon

[Tumeric] Antioxidant improves depression [3], cognition, but possible liver risks.

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Omega 3 (Fish oil)

Lithium SE, Anorexia, Major Depression, BP Depression, Bipolar, Depression, Age-related or non-specific decline, Treatments, Weight Gain, Autism, DMDD, Migraines, Non-specific Anxiety, Peripartum Depression, Borderline, ADHD, Inflammatory Depression, Acne, Psoriasis, Side Effects / Nancy Brandon

[Fish oil] For bipolar/unipolar depression [2], ADHD, [3], borderline pd [2], irritability, autism, [2], prevention of psychosis [1], dyslipidemia.

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Bupropion

First line depression, Major Depression, Treatments, Depression, Restless leg syndrome, Deepen Sleep, Nicotine, Methamphetamine, ADHD, Inflammatory Depression / Nancy Brandon

[Wellbutrin] First-line for depression (lacks weight-gain, sexual, cognitive, fatigue SEs; lack of WD). Safest antidepressant in bipolar. Treats nicotine but not as well as varenicline. Treats ADHD a little; RLS.

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