Dawn-Simulator
Improves morning fatigue and depression, particularly in winter. Can pair with lightbox for depression. Ideal for shift workers and night owls.
Depression
Lightbox
Very effective and well tolerated for depression regardless of season (also for bipolar, PTSD, bulimia, shift work)
Imipramine
[Tofranil] Ideal tricyclic for anxiety disorders, but sedating and anticholinergic effects.
Nortriptyline
[Pamelor] First-line tricyclic, low sedation/anticholinergic/hypotension risk. More
noradrenergic.
Amitriptyline
[Elavil] Third-line tricyclic, mix of serotonin/noripineprhine, more anticholinergic side effects.
Useful for pain and IBS.
Venlafaxine
[Effexor] Not ideal among the SNRIs (hypertension, WD risks, weight gain), but very effective for some and treats hot flashes in low doses.
Milnacipran
[$ Savella] Approved for fibromylagia in US and depression abroad (parent compound of
levomilnacipran).
Levomilnacipran
[$ Fetzima] Most noradrenergic of the SNRIs, good for fatigue, with side effect profile similar to
bupropion. Isomer of milnacipran (used in fibromylagia).