Dark-Therapy
Very effective for mania, prevents bipolar, deepens sleep. Mild weight loss.
Major Depression
Dawn-Simulator
Improves morning fatigue and depression, particularly in winter. Can pair with lightbox for depression. Ideal for shift workers and night owls.
Lightbox
Very effective and well tolerated for depression regardless of season (also for bipolar, PTSD, bulimia, shift work)
ECT
First-line for severe psychotic depression. In other cases of TRD, may prefer over TMS if severe. Also works for bipolar depression.
TMS
One of the most effective therapies for TRD. Well tolerated, improves cognition and neuroplasticity.
N-acetylcysteine
[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.
Imipramine
[Tofranil] Ideal tricyclic for anxiety disorders, but sedating and anticholinergic effects.
Trimipramine
[Sumontil] Third-line tricyclic, mix of serotonin/noripineprhine, more anticholinergic side
effects.