Memantine
[Namenda] Trichotillomania [1]. First-line for mod-severe Alzheimers (and Lew-Body, Parkinsons dementia). Possibly OCD, alcohol use, bipolar depression [3], autism [2].
BP Depression
Lightbox
Very effective and well tolerated for depression regardless of season (also for bipolar, PTSD, bulimia, shift work)
ECT
First-line for severe psychotic depression. In other cases of TRD, may prefer over TMS if severe. Also works for bipolar depression.
TMS
One of the most effective therapies for TRD. Well tolerated, improves cognition and neuroplasticity.
N-acetylcysteine
[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.
Asenapine
[Saphris] A good antipsychotic when others aren't tolerated. Treats bipolar mania/mixed [2] and
possibly bp-depression [4].
Cariprazine
[$ Vraylar] Top for schizophrenia [1] because it improves negative symptoms. Bipolar depression [2] + mania [1], unipolar augmentation [2], but low effect size in depressions.
Olanzapine-Fluoxetine
[Symbyax] Although weight gain is a problem, can be very effective for depression
(unipolar/bipolar) and mania/mixed.
Olanzapine-Fluoxetine Read More »
Lurasidone
[Latuda] BP-depression [1], depression with mixed features. Improves cognition in bipolar. Does not treat mania.
Lumateperone
[$ Caplyta] Among best tolerated antipsychotics for BP-depression [1], also unipolar-depression [2].
Unknown if helps mania. Low dopamine-blocking so well-tolerated in schizophrenia.