Bipolar Archives - Chris Aiken, MD

Memantine

Treatments, Autism, BP Depression, Dementia, OCD, Mixed, Trichotillomania / Chris

[Namenda] Trichotillomania [1]. First-line for mod-severe Alzheimers (and Lew-Body, Parkinsons dementia). Possibly OCD, alcohol use, bipolar depression [3], autism [2].

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Dark-Therapy

Hypnotics, Treatments, Hypnotic for Elderly, Weight Gain, Deepen Sleep, Mania, Mixed, Peripartum Depression, BP Cognition / Chris

Very effective for mania, prevents bipolar, deepens sleep. Mild weight loss.

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Lightbox

Fibromyalgia, First line depression, Depression, Bulimia, BP Depression, Male, Treatments, Deepen Sleep, Treatment Resistant Depression, PTSD, Negative symptoms, Peripartum Depression, Vascular Depression / Chris

Very effective and well tolerated for depression regardless of season (also for bipolar, PTSD, bulimia, shift work)

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ECT

BP Depression, Treatments, Treatment Resistant Depression, Psychotic Depression / Chris

First-line for severe psychotic depression. In other cases of TRD, may prefer over TMS if severe. Also works for bipolar depression.

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TMS

Treatments, BP Depression, Treatment Resistant Depression, Nicotine, OCD, Vascular Depression, Inflammatory Depression / Chris

One of the most effective therapies for TRD. Well tolerated, improves cognition and neuroplasticity.

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N-acetylcysteine

Alcohol, BP Depression, Age-related or non-specific decline, Bipolar, Treatments, Nicotine, OCD, Cannabis, Trichotillomania, Borderline, Negative symptoms, Inflammatory Depression, Cognition, Substance Use Disorders, Schizophrenia / Nancy Brandon

[NAC] For low-grade bipolar depression [3], protects kidneys on lithium, trichotillomania [1], cannabis and substance use disorders.

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Iloperidone

Bipolar, Treatments, Mania, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[$ Fanapt] Treats mania, unknown effects in depression, not a first-line option.

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Aripiprazole

First line schizophrenia, Major Depression, Bipolar, Treatments, Autism, Treatment Resistant Depression, Tics, Augmentation, Mania, Psychotic Depression, OCD, Psychotic symptoms, Mixed, Prolactinemia, Schizophrenia / Nancy Brandon

[Abilify] Among the better-tolerated antipsychotics, and best-studied for antidepressant
augmentation [1] (but doesn't treat bp-depression). Schizophrenia [1]

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Clozapine

Bipolar, Treatments, Treatment Resistant Schizophrenia, Mania, Mixed, Psychotic symptoms, Negative symptoms, Schizophrenia / Nancy Brandon

[Clozaril] Use in schizophrenia/schizoaffective after 2 failed antipsychotic trials. Prevents suicide
in psychotic disorders.

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Risperidone

Autism, Bipolar, Treatments, Treatment Resistant Depression, Mania, PTSD, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[Risperdal] Among most effective antipsychotics for schizophrenia [1]. Mania[3]. Augments
antidepressants in unipolar [3], PTSD [3], OCD [3].

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