Ginseng
Rapid benefits in energy, cognition, and ADHD that also build up over time (without tolerance or withdrawal).
ADHD
Desipramine
[Norpramin] Second-line tricyclic, low sedation/anticholinergic/hypotension risk. More
noradrenergic.
Solriamfetol
[$ Sunosi] Approved for narcolepsy but has bupropion-like properties and may treat ADHD.
Probiotics
For bipolar/unipolar depression [2], ADHD [3], anxiety [2], cognition [2], autism [2], weight loss [1], dyslipidemia, long COVID [1].
Vitamin D3
Mainly works when levels low: depression, ADHD, autism, sleep quality, negative symptoms of schizophrenia.
Coenzyme q10
For bipolar and unipolar depression [2], ADHD [3], autism [2], neurodevelopmental disorders [2], and energy in elderly.
Ginkgo
For TD [2], EPS [2], age related cognitive decline [2], GAD [3]. May help vascular depression.
Micronutrients
[Empowerplus] Although advertised in bipolar disorder, these branded multivitamins only have evidence in lability in ADHD. Prefer Enlyte for mood.
Saffron
Well-studied in depression [1], sleep, cognition. Small trials in ADHD [3], OCD [3], weight loss [3], sexual dysfunction [3].