Selegiline
[$ EMSAM] Skin patch MAOI, good to start with (low dose = no food interactions) but not as potent as older MAOIs.
Semaglutide
[$ Ozempic, Wegovy] Medium effective of the GLPs for weight loss (use if BMI >30 or > 27 with complications of obesity).
Esketamine
[$ Spravato] Strong, rapid medication for TRD [2], but works no better than placebo after a month and risky (used to model schizophrenia and autism). Ketamine IV is more effective but isn’t covered by insurance
Maca root
Maca root Sexual dysfunction Female Features Dosing 3,000 mg/d Management $3-10/mth. Has testosterone- and estrogen-like effects EMR Text
Inositol
For bipolar depression (synergistic with omega-3) [3], bulimia [2], psoriasis on lithium [1]. Studied in children.
Probiotics
For bipolar/unipolar depression [2], ADHD [3], anxiety [2], cognition [2], autism [2], weight loss [1], dyslipidemia, long COVID [1].
Citicoline
For mood disorders with meth/cocaine abuse [1], age-related cognitive decline [1], and post-stroke depression [2]