Baclofen
Muscle relaxant can be very effective for alcohol [2] but has small misuse potential. Also binge eating [3].
Medication
Acamprosate
[Campral] Well tolerated but low efficacy for alcohol use disorder. May make WD symptoms less aversive.
Disulfiram
(Antabuse) Treats alcoholism by raising the chemical responsible for hangovers. Very effective if patient takes it.
Methylphenidate
First-line stimulant (more neuroprotective and safer for mental health than amphetamine). May help apathy in old age but not for depression.
Amphetamine
Amphetamine Stimulant (dopamine-norepinephrine reuptake inhibitor and releaser; serotonin reuptake inhibition) Features Dosing Dextroamphetamine Dextro is the more potent of the
Modafinils
[Provigil, Nuvigil] Wakefulness-promoting agents FDA approved for fatigue associated with sleep apnea or shift work. Also treats bipolar depression (2), unipolar depression (3), ADHD (3), and cocaine use disorder.
Pramipexole
[Mirapex] Dopamine agonist with powerful benefits in unipolar and bipolar depression, also restless leg syndrome.