Bipolar-Safe Archives - Page 12 of 13

Eszopiclone

[Lunesta]Among the z-hypnotics, has the most benzo-like properties, and can augment antidepressants (short term) in depression and GAD.

[Ambien] Potent z-hypnotic.

[Sonata] Z-hypnotic with the lowest risk of morning sedation.

Although over the counter, the prescription version (hydroxyzine) is safer with fewer anticholinergic risks.

A well tolerated option for mania, but third-line due to few trials.

Anti-viral improves cognition in bipolar and schizophrenia but only if herpes HSV+

Think of it as low-potency ketamine. Rapid acting as Auvelity in depression, or as monotherapy (3rd line) in bipolar depression. Abuse potential.

Muscle relaxant can be very effective for alcohol [2] but has small misuse potential. Also binge eating [3].

[Campral] Well tolerated but low efficacy for alcohol use disorder. May make WD symptoms less aversive.

(Antabuse) Treats alcoholism by raising the chemical responsible for hangovers. Very effective if patient takes it.