CAM (modulates stress hormones in the HPA-axis, protects hippocampus)

  • Cognition in bipolar
  • Reduces stress response

Dosing

Sensoril 250mg/day x7days then 500mg/day.

Management

Advise patient to get the Sensoril preparation which comes in several brands. Safety/efficacy of other ashwagandhas not known and some have liver risks. It is not well-studied for cognition in bipolar (in a small trial it helped intuitive thinking, processing speed, facial recognition), but little else works there. It may reduce stress-reactivity.

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