Ramelteon (Rozerem)
Hypnotic (melatonin agonist)
- Hypnotic (safe in elderly and sleep apnea)2
- May prevent bipolar depression
Features
Dosing
8mg/night. Can take PRN, but may work better when taken at the same time nightly. Works by setting the circadian rhythm rather than causing sedation.
Management
TOLERABILITY: Headache, nausea, daytime fatigue. May be best not to take melatonin with it (this is not clear).
RISKS: None
EMR Text
Insomnia
Ramelteon use based on FDA approval for insomnia.
Ramelteon side effects reviewed with patient.
Insomnia in Sleep Apnea
Ramelteon use based on FDA approval for insomnia, and studies supporting its safety in sleep apnea (Gooneratne NS et al, J Clin Sleep Med. 2010;6(6):572-80).
Ramelteon side effects reviewed with patient.