Lemborexant ( $ Dayvigo)

Hypnotic (Orexin antagonist)

Dosing

5mg 1 qhs prn insomnia (do not take within 30min of eating) (max 10mg/night)

Management

Improves next-day cognition. No known abuse/dependence. Studied in elderly with safe results, no fall risk. Blocks oxerin (involved in wakefullness). Interactions may be possible (e.g. diltiazem) through CYP3A.

EMR Text