Diphenhydramine (Benadryl)

Hypnotic (antihistamine)

Dosing

25-50 mg hs

Management

SE: cognitive impairment, anticholinergic (drying, constipation), weight gain.

Prefer hydroxyzine which is prescription but has fewer side effects. If your patient likes to take Tylenol PM or similar med for sleep, tell them to skip the liver/stomach damaging pain med and just take OTC benadryl for sedative effects

EMR Text