Lurasidone
[Latuda] BP-depression [1], depression with mixed features. Improves cognition in bipolar. Does not treat mania.
[Latuda] BP-depression [1], depression with mixed features. Improves cognition in bipolar. Does not treat mania.
[$ Caplyta] Among best tolerated antipsychotics for BP-depression [1], also unipolar-depression [2].
Unknown if helps mania. Low dopamine-blocking so well-tolerated in schizophrenia.
[Seroquel] Unique antipsychotic – metabolized into an antidepressant so treats unipolar
depression (and GAD) as monotherapy. Top for TRD [1]. Deepens sleep. Tolerability poor, but among the most
effective options for BP-depression [1], BP-anxiety [2], mania, mixed.
[$ Cobenfy] First-line antipsychotic for schizophrenia (lacks long-term risks, though GI issues a problem at start). Not effective in other disorders.
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