Medical

Trazodone

Hypnotics in Sleep Apnea, Major Depression, Agitation in Dementia, Hypnotics, Depression, Treatments, Bulimia, Sleep apnea, Deepen Sleep, Negative symptoms, Sleep / Nancy Brandon

Deepens sleep quality in low doses, but under-utlilized as an antidepressant, where it can be very effective and tolerable if dosed at night.

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Buspirone

Generalized Anxiety, Treatments, SSRI-Induced, Anxious Depression, Bruxism, Premenstrual Dysphoria, Sexual Dysfunction / Nancy Brandon

Treats anxiety (GAD). Augments in depression but only if anxious. Also improves sexual dysf, bruxism, irritability, PMDD

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Modafinils

Major Depression, Treatments, BP Depression, Sleep apnea, Methamphetamine, BP Cognition, Cocaine, ADHD, Cognition / Nancy Brandon

[Provigil, Nuvigil] Wakefulness-promoting agents FDA approved for fatigue associated with sleep apnea or shift work. Also treats bipolar depression (2), unipolar depression (3), ADHD (3), and cocaine use disorder.

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Atomoxetine

Treatments, Sleep apnea, Methamphetamine, ADHD / Nancy Brandon

Good for ADHD with anxiety, but least effective among FDA options for ADHD. Avoid in bipolar.

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Pramipexole

Major Depression, First line BP depression, BP Depression, Depression, Bipolar, Restless leg syndrome, Treatment Resistant Depression, Inflammatory Depression / Chris

[Mirapex] Dopamine agonist with powerful benefits in unipolar and bipolar depression, also restless leg syndrome.

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