Major Depression Archives - Page 3 of 9

Desvenlafaxine

Major Depression, Depression, Treatments, Panic, Anxiety, Social Anxiety / Nancy Brandon

[Pristiq] Safest SNRI.

Brexpiprazole

Agitation in Dementia, Treatments, Treatment Resistant Depression, PTSD, Psychotic symptoms, Schizophrenia / Nancy Brandon

[$ Rexulti] Well tolerated for antipsychotics, treats unipolar-depression, ptsd, but not bp-
depression and not mania.

Brexpiprazole Read More »

Aripiprazole

First line schizophrenia, Major Depression, Bipolar, Treatments, Autism, Treatment Resistant Depression, Tics, Augmentation, Mania, Psychotic Depression, OCD, Psychotic symptoms, Mixed, Prolactinemia, Schizophrenia / Nancy Brandon

[Abilify] Among the better-tolerated antipsychotics, and best-studied for antidepressant
augmentation [1] (but doesn't treat bp-depression). Schizophrenia [1]

Aripiprazole Read More »

Risperidone

Bipolar, Treatments, Autism, Treatment Resistant Depression, Mania, PTSD, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[Risperdal] Among most effective antipsychotics for schizophrenia [1]. Mania[3]. Augments
antidepressants in unipolar [3], PTSD [3], OCD [3].

Risperidone Read More »

Cariprazine

First line schizophrenia, Treatments, BP Depression, Bipolar, First line mania, Treatment Resistant Depression, Mania, Mixed, Psychotic symptoms, Negative symptoms, Schizophrenia / Nancy Brandon

[$ Vraylar] Top for schizophrenia [1] because it improves negative symptoms. Bipolar depression [2] + mania [1], unipolar augmentation [2], but low effect size in depressions.

Cariprazine Read More »

Olanzapine-Fluoxetine

Treatments, BP Depression, Bipolar, Treatment Resistant Depression / Nancy Brandon

[Symbyax] Although weight gain is a problem, can be very effective for depression
(unipolar/bipolar) and mania/mixed.

Olanzapine-Fluoxetine Read More »

Ziprasidone

Bipolar, Treatments, Sleep apnea, Treatment Resistant Depression, Mania, Psychotic symptoms, Mixed, Schizophrenia / Nancy Brandon

[Geodon] Among best antipsychotics for low weight/diabetes risk. Treats mania/mixed; possibly
helps depression in unipolar and bipolar.

Ziprasidone Read More »

Olanzapine

Treatments, Second line schizophrenia, Bipolar, Treatment Resistant Schizophrenia, Psychotic Depression, Mania, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[Zyprexa] High efficacy in schizophrenia [2], so use before moving to clozapine. Mania [2], augmentation in unipolar [3], PTSD [3].

Olanzapine Read More »

Lumateperone

BP Depression, Bipolar, Treatments, Treatment Resistant Depression, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[$ Caplyta] Among best tolerated antipsychotics for BP-depression [1], also unipolar-depression [2].
Unknown if helps mania. Low dopamine-blocking so well-tolerated in schizophrenia.

Lumateperone Read More »

Quetiapine

Generalized Anxiety, Treatments, BP Depression, Bipolar, Deepen Sleep, First line mania, Anxiety, Treatment Resistant Depression, OCD, Mania, Mixed, Psychotic symptoms, Anxious Depression, BP Anxiety, Schizophrenia / Nancy Brandon

[Seroquel] Unique antipsychotic – metabolized into an antidepressant so treats unipolar
depression (and GAD) as monotherapy. Top for TRD [1]. Deepens sleep. Tolerability poor, but among the most
effective options for BP-depression [1], BP-anxiety [2], mania, mixed.

Quetiapine Read More »