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Chris Aiken, MD

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Chris Aiken, MD

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Anxious Depression

Imipramine

Major Depression, Generalized Anxiety, Depression, Treatments, Panic, Anxiety, Treatment Resistant Depression, Binge Eating, Anxious Depression, Eating Disorders / Nancy Brandon

[Tofranil] Ideal tricyclic for anxiety disorders, but sedating and anticholinergic effects.

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Quetiapine

Generalized Anxiety, Bipolar, Treatments, BP Depression, Anxiety, Treatment Resistant Depression, Deepen Sleep, First line mania, Mania, OCD, Psychotic symptoms, Anxious Depression, Mixed, BP Anxiety, Schizophrenia / Nancy Brandon

[Seroquel] Unique antipsychotic – metabolized into an antidepressant so treats unipolar
depression (and GAD) as monotherapy. Top for TRD [1]. Deepens sleep. Tolerability poor, but among the most
effective options for BP-depression [1], BP-anxiety [2], mania, mixed.

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Phenelzine

Major Depression, Treatments, Depression, Treatment Resistant Depression, Anxiety, Social Anxiety, Anxious Depression / Nancy Brandon

[Nardil] Ideal MAOI for anxiety, and more effective for social anxiety than SSRIs.

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Probiotics

Generalized Anxiety, Female, Major Depression, Depression, BP Depression, Age-related or non-specific decline, Treatments, Autism, Bipolar, Treatment Resistant Depression, Anxiety, Deepen Sleep, Anxious Depression, Borderline, Negative symptoms, Peripartum Depression, Sleep, ADHD, Long COVID, Inflammatory Depression, Cognition, Schizophrenia, Sexual Dysfunction / Nancy Brandon

For bipolar/unipolar depression [2], ADHD [3], anxiety [2], cognition [2], autism [2], weight loss [1], dyslipidemia, long COVID [1].

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Rhodiola rosea

Major Depression, Generalized Anxiety, Depression, Treatments, Anxiety, Non-specific Anxiety, Anxious Depression / Nancy Brandon

Herb that helps with mild depression and stress management.

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l-Theanine

Hypnotics, Major Depression, Hypnotic for Elderly, Depression, Age-related or non-specific decline, Treatments, Deepen Sleep, Anxiety, OCD, Augmentation, Non-specific Anxiety, Anxious Depression, Negative symptoms, Cognition, Schizophrenia / Nancy Brandon

Extract of green tea. Depression [3], sleep [2], schizophrenia (neg/anx) [2], OCD [3], cognition [3].

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Lavender

Hypnotics, Major Depression, Generalized Anxiety, Depression, Treatments, Hypnotic for Elderly, Anxiety, Non-specific Anxiety, Anxious Depression / Nancy Brandon

[Silexan] First-line for generalized anxiety, Prescription and approved outside US. Well-tolerated, safe in bipolar.

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Prazosin

Agitation in Dementia, Major Depression, Treatments, Alcohol, Deepen Sleep, PTSD, Nightmares, Anxious Depression / Nancy Brandon

[Minipress] First-line for PTSD, treats nightmares and daytime symptoms.

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Gepirone

Major Depression, Generalized Anxiety, Treatments, Depression, Anxiety, Anxious Depression / Nancy Brandon

[$ Exxua] Similar to buspirone but not as useful (costly, requires EKG testing, failed in most depression trials)

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Mirtazapine

Major Depression, Treatments, Hypnotic for Elderly, Deepen Sleep, OCD, Anxious Depression, Methamphetamine, Sleep / Nancy Brandon

[Remeron] Ideal for elderly and depression with GI problems, insomnia, anxiety.

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