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Chris Aiken, MD

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Chris Aiken, MD

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Anxiety

Brexpiprazole

Agitation in Dementia, Treatments, Treatment Resistant Depression, PTSD, Psychotic symptoms, Schizophrenia / Nancy Brandon

[$ Rexulti] Well tolerated for antipsychotics, treats unipolar-depression, ptsd, but not bp-
depression and not mania.

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Risperidone

Treatments, Autism, Bipolar, Treatment Resistant Depression, Mania, PTSD, Mixed, Psychotic symptoms, Schizophrenia / Nancy Brandon

[Risperdal] Among most effective antipsychotics for schizophrenia [1]. Mania[3]. Augments
antidepressants in unipolar [3], PTSD [3], OCD [3].

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Quetiapine

Generalized Anxiety, Treatments, BP Depression, Bipolar, Anxiety, Treatment Resistant Depression, Deepen Sleep, First line mania, OCD, Mania, Mixed, Psychotic symptoms, Anxious Depression, BP Anxiety, Schizophrenia / Nancy Brandon

[Seroquel] Unique antipsychotic – metabolized into an antidepressant so treats unipolar
depression (and GAD) as monotherapy. Top for TRD [1]. Deepens sleep. Tolerability poor, but among the most
effective options for BP-depression [1], BP-anxiety [2], mania, mixed.

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Tranylcypromine

Major Depression, Depression, Treatments, Panic, Anxiety, Social Anxiety, Treatment Resistant Depression / Nancy Brandon

[Parnate] Ideal MAOI for tolerability, with low weight/sedation problems. May treat panic.

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Phenelzine

Major Depression, Depression, Treatments, Anxiety, Social Anxiety, Treatment Resistant Depression, Anxious Depression / Nancy Brandon

[Nardil] Ideal MAOI for anxiety, and more effective for social anxiety than SSRIs.

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Iscarboxazid

Major Depression, Treatments, Depression, Anxiety, Social Anxiety / Nancy Brandon

[Marplan] Third-line among the MAOIs (least studied of the bunch).

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Selegiline

Major Depression, Treatments, Panic, Depression, Anxiety / Nancy Brandon

[$ EMSAM] Skin patch MAOI, good to start with (low dose = no food interactions) but not as potent as older MAOIs.

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Inositol

Bipolar, Treatments, Bulimia, BP Depression, Panic, Eating Disorders, Psoriasis / Nancy Brandon

For bipolar depression (synergistic with omega-3) [3], bulimia [2], psoriasis on lithium [1]. Studied in children.

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Probiotics

Major Depression, Generalized Anxiety, Female, Bipolar, Depression, BP Depression, Age-related or non-specific decline, Treatments, Autism, Anxiety, Deepen Sleep, Treatment Resistant Depression, Anxious Depression, Borderline, Negative symptoms, Peripartum Depression, Sleep, ADHD, Long COVID, Cognition, Inflammatory Depression, Schizophrenia, Sexual Dysfunction / Nancy Brandon

For bipolar/unipolar depression [2], ADHD [3], anxiety [2], cognition [2], autism [2], weight loss [1], dyslipidemia, long COVID [1].

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Rhodiola rosea

Major Depression, Generalized Anxiety, Depression, Treatments, Anxiety, Anxious Depression, Non-specific Anxiety / Nancy Brandon

Herb that helps with mild depression and stress management.

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