Phosphatidylersine (PS)
CAM (antiinflammatory, modulating stress hormones in the HPA axis, influencing serotonin and dopamine)
- ADHD3
- Age related cognitive decline2
- Early stages of dementia2
Features
Dosing
Childhood ADHD: 200-300 mg/day
Adult cognition: 300-600 mg/day
Can start at 300 mg qd. Wait 4 weeks to see response.
Management
Often used in combination with omega-3 (once available as Vayarin and Vayacog supplements that way).
EMR Text
ADHD
Phosphatidylersine use based on randomized controlled trials in ADHD (Hirayama S et al, J Hum Nutr Diet 2014;27 Suppl 2:284-91).
Phosphatidylersine side effects reviewed with patient.
Cognition
Phosphatidylersine use based on randomized controlled trials in age related cognitive decline and dementia (Cenacchi T et al, Aging (Milano). 1993;5(2):123-133).
Phosphatidylersine side effects reviewed with patient.